The Science of Kambo
What is in the kambo secretion?
Kambo contains a cocktail of bioactive peptides, each with a specific function in the human body. These compounds—formed by linking amino acids—are recognized by the body and interact with its systems at a cellular level. When introduced, the peptides open cell receptors and trigger natural responses like detoxification, immune modulation, and nervous system support.
Many of these peptides have been studied for their potential in medical applications, particularly in pain relief, antimicrobial activity, and neurological balance. Over 70 patents related to Kambo peptides have been filed, mostly in the U.S., by pharmaceutical researchers.
As the secretion of the Phyllomedusa Bicolor frog becomes more widely known, experienced practitioners continue to explore new methods for working with this powerful natural substance in ways that are accessible and safe. Whether through traditional application or modern adaptations like auricular (ear) Kambo, the peptides in this secretion offer deep physical and energetic support.
Kambo Peptides
Phyllomedusin – A neuropeptide that stimulates the intestines, salivary glands, and digestive system, helping flush deep toxins and support detoxification.
Phyllokinin – Improves circulation by widening blood vessels and increasing the permeability of the blood-brain barrier, allowing beneficial compounds to pass through more easily.
Phyllocaerulein – A natural pain-relieving peptide that supports sedation, thermoregulation, and emotional balance. It helps reduce blood pressure and calms the nervous system.
Phyllolitorin – Supports digestion by stimulating stomach acid secretion and muscle contraction in the gastrointestinal tract.
Dermorphin – A powerful peptide with opiate-like effects, up to 40 times stronger than morphine on specific opioid receptors, without the addictive risks.
Tryptophyllins – Offer antimicrobial protection by inhibiting harmful pathogens such as Candida, Staphylococcus, and E. coli.
Deltorphin – Binds to opioid receptors and is being researched for its potential use in pain relief and cancer treatment.
Dermaseptin & Adenoregulin (B2) – Antimicrobial peptides that target bacteria, fungi, and protozoa. Early studies show promise in their ability to inhibit cancer cell growth and support immune health.
